We Started LiveO2 Because Medicine Said There Was Nothing Left to Do
Mark Squibb’s son had a neurological injury. The doctors said they’d done everything they could. Mark — an engineer — decided that wasn’t good enough.
An Engineer’s Problem. An Engineer’s Solution.
Mark Squibb is an electrical engineer. Not a doctor, not a supplement marketer, not a biohacker. He thinks in systems — power, plumbing, cause and effect.
Then his family got sick. One of his children suffered a neurological injury. Mark had also been noticing his own body slowing down faster than he wanted. He went to doctors. They ran tests. They did what they could.
And then they said there was nothing left to do.
“Some people in my family got sick and then one of my kids had a neurological injury. I had been looking at oxygen for personal use because I was getting old faster than I wanted to.”— Mark Squibb, LiveO2 Founder
An engineer doesn’t accept “nothing left to do.” He asks: where’s the bottleneck? What’s the system not doing? Can it be fixed?
Mark’s research led him to the work of Manfred von Ardenne — a German physicist who spent decades studying how oxygen actually moves through the body. Von Ardenne had discovered that the problem wasn’t getting oxygen into the lungs. The real bottleneck was getting oxygen from the blood plasma into the tissues themselves.
Mark combined three principles nobody else had assembled together: exercise creates cardiovascular pressure that forces open dormant capillaries; breathing low oxygen triggers the body to push even harder; then switching to high oxygen floods the pathways the body just forced open. That combination — Adaptive Contrast — is what he built.
He built it for his family first. Then other families asked for it. Then clinics. Then athletes. Then researchers.
“Get oxygen where the body needs it. Let the body do the rest.”— Mark Squibb, LiveO2 Founder
Three Things We Know to Be True About Oxygen and the Body
The body already knows how to heal
It just needs the right conditions. Oxygen is one of those conditions. Most of what we call “chronic illness” is a delivery problem, not a broken system.
Exercise activates what rest can’t
Movement drives oxygen deeper into tissue than passive therapy alone. The cardiovascular pressure from exercise opens capillaries that stay shut when you’re sitting still.
Contrast is the mechanism
Switching between low-oxygen and high-oxygen states during exercise triggers emergency vasodilation, EPO production, and deep tissue saturation. That’s the science behind Adaptive Contrast.
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Built for People Who Take Their Biology Seriously
Performance Athletes
Altitude simulation without altitude. Faster recovery, higher VO₂ max, and a cardiovascular edge that standard training can’t produce.
Training & RecoveryChronic Illness & Fatigue
When standard treatments plateau. Cellular oxygen delivery for conditions — long COVID, fibromyalgia, brain fog — that resist conventional care.
Chronic ConditionsLongevity & Aging
Mitochondrial function declines with age. IHHT has been shown in peer-reviewed research to slow that decline and improve cardiovascular markers.
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LiveO2 is installed in Bulletproof Labs and performance centers worldwide. Dual-user systems available for clinical and professional use.
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Mark Squibb — Engineer, Father, Founder
Mark is an electrical engineer — but his real discipline is working with nature, not against it. His off-grid home at 7,500 feet in the Colorado Rockies has no furnace, no air conditioner, no utility bill. It harvests the sun, collects rainwater, and generates more electricity than the family uses. Not because he’s an idealist — because he’s an engineer who looked at how natural systems actually work and designed accordingly.
That same instinct drove LiveO2. When conventional medicine ran out of answers for his family, Mark didn’t reach for pharmaceuticals. He looked at what the body already runs on — oxygen, the molecule every cell depends on — and engineered a way to deliver it exactly when and how the body needs it most. Not a drug. Not a pressure chamber. Just nature’s most powerful molecule, precisely applied.
A wildfire took everything in 2012. Mark woke up the next morning with no home, no debt, and a blank slate. He called it a cleansing. The family rebuilt together — every beam, every circuit, every system. That experience is baked into how he runs LiveO2: resilience through design, not dependence. The mission hasn’t changed since day one.
Watch Mark explain how it startedMark’s house runs on passive solar — the roof is engineered as a 6,000 sq ft mirror that reflects sunlight onto vertical solar panels, generating 140% more energy than conventional mounting. No furnace. No AC. The same principle guides LiveO2: don’t fight the body’s systems, amplify what nature already provides.
The High Park wildfire swept through in 2012 and took their home, outbuildings, and everything they owned. Mark and Debbie rallied their three sons — Hunter, Tanner, and Dion — and rebuilt from scratch. Mark called it a life reset. “If you get a clean slate, where do you want to begin?” The answer shaped how he runs LiveO2 to this day.
LiveO2 was built for the Squibb family before it was a product. The system still sits in their home gym on the mountain. Mark coaches his sons on the same equipment he ships to customers worldwide. “We do everything together — doesn’t matter if it’s pouring concrete or building a house.” That ethos runs through the company.
“The fire was traumatic, a huge loss — but it was also, in the biblical sense, a cleansing by fire. You wake up and it’s like start over. But that’s not always bad. It’s a reset. And it sure made the boys stronger.”— Mark Squibb, Founder of LiveO2
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