Legacy Protocols

These pro­to­cols were extract­ed and updat­ed from von Ardenne’s book, Oxy­gen Mul­ti­step Ther­a­py. They are not med­ical advice; they are spe­cif­ic exer­cise rec­om­men­da­tions designed to aug­ment oxy­gen lev­els tar­get­ing spe­cif­ic body sys­tems, like the vas­cu­lar sys­tem and immune sys­tem, using dif­fer­ent com­bi­na­tions of non-med­ical approach­es.

  • First Time - Before


  • During


  • After


Video Tutor

Advanced Protocols

Before mov­ing on to the advanced pro­to­cols, be sure you can com­fort­ably get through the “Quick” pro­to­col as described near the end of the arti­cle “The LiveO2 Pro­to­cols.” The Quick pro­to­col will help you become accus­tomed to reg­u­lar exer­cise, build sta­mi­na and restore cel­lu­lar activ­i­ty. Once you’re able to exer­cise for a full fif­teen min­utes with ease, you can choose one or more of the advanced pro­to­cols to address spe­cif­ic issues or achieve your par­tic­u­lar goals.

The LiveO2 Adap­tive Con­trast® sys­tem pro­vides both oxy­gen-rich air and oxy­gen-deprived air. Alter­nat­ing between these two modes of oper­a­tion while exer­cis­ing is the key to dri­ving oxy­gen deep into the body.


Sprint” implies high ener­gy out­put, in essence, to “give it all you’ve got.” This may be done on an exer­cise bike, tread mill or sim­i­lar exer­cise equip­ment.

The term “tar­get heart rate” means ((220 — your_age) * .7). This is just a guide­line; don’t wor­ry if you are unable to get your heart rate up to the cal­cu­lat­ed rate. As with all exer­cise pro­grams, start slow and work your way up. Over time, your per­for­mance will tend to improve.

Preparation Protocol

Use this pro­to­col for at least two weeks before you incor­po­rate oxy­gen con­trast into your reg­u­lar exer­cise ses­sion. The intent of the pro­to­col is to accli­mate the body to phys­i­cal exer­tion with low­er oxy­gen pres­sure. The body adapts to hypo­bar­ic exer­cise by cre­at­ing more red blood cells, improv­ing lung func­tion and dilat­ing the vas­cu­lar sys­tem.

If you are over­ly sen­si­tive to breath­ing “thin” air, you may expe­ri­ence headache, loss of appetite, mild insom­nia or oth­er forms of hypox­ic dis­com­fort. If you expe­ri­ence any of these or oth­er symp­toms, con­sult your health care provider before con­tin­u­ing this pro­to­col.

  • Set the sys­tem to -O2
  • Exer­cise at a mod­er­ate to strong pace for 15 min­utes
  • At the end of the 15 min­utes, sprint for 30 sec­onds
  • Switch to +O2 until you’ve recov­ered
  • Sprint on +O2 for 30 sec­onds
  • Recov­er
  • Sprint on +O2 for 30 sec­onds
  • Recov­er and cool down on oxy­gen for 5 min­utes

Hypobaric Recovery

Hypox­ic dis­com­fort (alti­tude sick­ness) is gen­er­al­ly caused by inflam­ma­tion. The goal of this pro­to­col is to reduce the inflam­ma­tion.

Recovery Protocol

  • In +O2 mode, bring your heart rate up to 110 beats per minute or high­er (about five min­utes of exer­cise is usu­al­ly suf­fi­cient). You will like­ly feel mul­ti­ple exer­tion chal­lenges dur­ing this phase
  • Stay on oxy­gen until you feel com­fort­able and your oxy­gen sat­u­ra­tion reach­es and holds at 99% for 3 min­utes or until 15 min­utes have elapsed, whichev­er occurs first
  • If your oxy­gen sta­bi­lizes at 99%, then pre­pare to do a hypox­ic sprint. The goal is to increase your heart rate fur­ther and then switch back to oxy­gen to dri­ve the oxy­gen deep­er into your body
  • Switch to -O2 and sprint for 30 sec­onds
  • Switch to +O2 until you’ve recov­ered
  • Repeat the pre­vi­ous two steps up to three more times or until you have recov­ered, or until the oxy­gen reser­voir is emp­ty.

Respiratory Inertia Exercise

Hypo­bar­ic exer­cise caus­es sev­er­al ben­e­fi­cial effects which occur nat­u­ral­ly for peo­ple who live at high alti­tudes:

  • It stim­u­lates the devel­op­ment of lung tis­sue
  • It stim­u­lates an increase in blood-oxy­gen trans­port capac­i­ty with a high­er num­ber red blood cells
  • The ele­vat­ed red blood cell counts increase the cir­cu­lat­ing reserve of oxy­gen which helps to delay the aer­o­bic to anaer­o­bic ener­gy pro­duc­tion dur­ing burst exer­tion
  • Oth­er opti­miza­tions occur, but they are not under­stood at this time.

This pro­to­col tran­si­tions the body from an aer­o­bic to an anaer­o­bic state, and back again. Our expe­ri­ence indi­cates that brief anaer­o­bic sprints stim­u­late adap­tive respons­es in the body, even though the dura­tion of anaer­o­bic strain is very short, usu­al­ly less than five min­utes in a fif­teen minute exer­cise ses­sion.


  • Warm up until you reach your tar­get pulse rate
  • Put on your mask and con­nect to the oxy­gen
  • Mon­i­tor your pulse and increase inten­si­ty to main­tain your tar­get pulse rate
  • Hold your tar­get pulse rate for 6 min­utes on +O2
  • Switch to -O2 and main­tain a con­stant lev­el of exer­tion (your pulse and strain will increase)
  • Hold this lev­el until your O2 sat­u­ra­tion reach­es 90% or drops down to 85% (or until you feel it’s “too much”)
  • Switch back to +O2
  • Hold this high oxy­gen for 3 min­utes
  • Repeat the -O2 inter­val
  • Fin­ish the ses­sion on +O2 until 15 min­utes are com­plete
  • Con­tin­ue breath­ing oxy­gen until pulse drops below 100 bpm.

Saturation Stress Exercise

This pro­to­col opti­mizes the body’s use of “stored” oxy­gen by stress­ing the body’s de-sat­u­ra­tion and re-sat­u­ra­tion mech­a­nisms.

De-sat­u­ra­tion delays the onset of anaer­o­bic ener­gy pro­duc­tion by using blood-bound oxy­gen to pro­long aer­o­bic per­for­mance.

Re-sat­u­ra­tion exer­cise accel­er­ates recov­ery from an anaer­o­bic metab­o­lism back to aer­o­bic. For an unknown rea­son, it seems to accel­er­ate the tran­si­tion from anaer­o­bic back to aer­o­bic ener­gy.

This pro­to­col adds anoth­er con­trol para­me­ter: the tar­get de-sat­u­ra­tion lev­el. As you exer­cise, your body should be able to tol­er­ate low­er de-sat­u­ra­tion lev­els dur­ing these inter­vals. As this lev­el goes down, your body is using more of its blood-bound oxy­gen to delay the tran­si­tion from aer­o­bic to anaer­o­bic ener­gy pro­duc­tion. When you switch to low oxy­gen, your body will use “stored cir­cu­lat­ing oxy­gen” to pro­vide ener­gy.

This pro­to­col estab­lish­es a min­i­mum sat­u­ra­tion lev­el, defined as the min­i­mum O2 sat­u­ra­tion that you can tol­er­ate while under exertion.The low­est lev­el observed in an ath­lete was 61%, although most indi­vid­u­als capa­ble of sus­tained phys­i­cal exer­tion are capa­ble of 75–85%.

To test your per­son­al de-sat­u­ra­tion tol­er­ance:

  • Warm up until you reach your tar­get pulse rate
  • Con­tin­ue anoth­er 5 min­utes to make sure the cir­cu­la­to­ry sys­tem is ful­ly adapt­ed to the strain
  • Switch to -O2
  • Mon­i­tor your pulse and O2 sat­u­ra­tion
  • Sprint at 90% of your max­i­mum abil­i­ty
  • Mon­i­tor your pulse and oxy­gen sat­u­ra­tion lev­els
  • Con­tin­ue until you reach exer­tion tol­er­ance point
  • Record the min­i­mum sat­u­ra­tion and high­est pulse at the end

Desaturation Exercise Method

  1. Warm up until you reach your tar­get pulse rate
  2. Put on the mask and con­nect to the oxy­gen
  3. Exer­cise for 3 min­utes, increas­ing inten­si­ty to main­tain your tar­get pulse rate
  4. Switch to -O2
  5. Sprint until you reach res­pi­ra­to­ry tol­er­ance (note desat­u­ra­tion lev­el and exer­tion delay)
  6. Switch back to +O2 for 3 min­utes (note how long it takes to return to 99%)
  7. Resume at step 5, stop exer­cis­ing after 15 min­utes
  8. Con­tin­ue breath­ing oxy­gen until your pulse drops to 100 bpm or low­er.

Clearing Inflammation

Use this pro­to­col after your work­out or after a peri­od of hard phys­i­cal work to clear exer­tion waste and restore blood flow. This pro­to­col usu­al­ly cuts recov­ery time in half. It works by clear­ing inflam­ma­tion which retards recov­ery.

Protocol Goals

  • To restore blood flow to trau­ma­tized tis­sues and enable heal­ing, revers­ing the inflam­ma­tion trig­gered dur­ing exer­cise
  • To reduce sys­temic waste accu­mu­la­tion to avoid over-exer­cise fatigue
  • To flush post-per­for­mance lac­tic acid to pre­vent sore­ness
  • To max­i­mize body-wide dis­solved oxy­gen to accel­er­ate heal­ing in con­nec­tive tis­sue, thus reduc­ing micro-trau­ma accu­mu­la­tion

Post-Performance Protocol

  1. Warm up until you reach your tar­get pulse rate *
  2. Exer­cise for 8 min­utes at your pre­ferred aer­o­bic out­put
  3. Do the fol­low­ing steps three times:
    1. Switch to -O2 and do a 30 sec­ond sprint
    2. Use -O2 for the first 15 sec­onds, then switch to +O2 for 15 sec­onds
    3. Recov­er on oxy­gen
    4. If you feel bet­ter than when you start­ed, per­form these steps again; oth­er­wise, stop now and skip to step 5 below.
  4. Stop exer­cis­ing at 12 min­utes
  5. Con­tin­ue breath­ing oxy­gen until your pulse rate drops to 100 bpm or less.

* If you feel tired, use +O2 set­ting. If you feel “strong,” then use -O2 to accel­er­ate the warm-up until your heart rate gets to your nor­mal aer­o­bic exer­cise lev­el.


When the body expe­ri­ences pro­tract­ed peri­ods of heavy phys­i­cal demand, a phys­i­o­log­i­cal pat­tern emerges:

  • Over-exer­cis­ing cre­ates stress;
  • Stress trig­gers cap­il­lary chokes (See Oxy­gen Mul­ti­step Ther­a­py)
  • Cap­il­lary chokes lim­its blood flow, which in turn increas­es reliance on anaer­o­bic metab­o­lism
  • Anaer­o­bic metab­o­lism increas­es the accu­mu­la­tion of lac­tic acid in mus­cles and oth­er tis­sues
  • Excess lac­tic acid and lim­it­ed blood flow locks in the anaer­o­bic metab­o­lism
  • This sequence results in ever increas­ing fatigue and dis­com­fort over time.

The result­ing anaer­o­bic state is eas­i­ly resolved with the fol­low­ing:

  • Exer­cise until your pulse rate is greater than 120 beats per minute
  • Begin use of oxy­gen
  • Exer­cise for 15 min­utes
  • Repeat if nec­es­sary

This pro­to­col nor­mal­ly resolves fatigue in one ses­sion.


The release of lac­tic acid from tis­sues may over­load the Cori Cycle, result­ing in fast bow­el for up to three hours after your ses­sion.

Brain Oxygenation

This pro­to­col tar­gets restora­tion of oxy­gen to the head to help resolve inflam­ma­tion in the brain, eyes and ears. Many con­di­tions involve inflam­ma­tion in the brain and sen­so­ry organs:

  • Tin­ni­tus – inflam­ma­tion in the audi­to­ry pro­cess­ing of the inner ear
  • Menieres/Vertigo – inflam­ma­tion in the bal­ance cen­ter of the ear
  • Brain Fog – Inflam­ma­tion in the con­scious pro­cess­ing cen­ters of the brain
  • Con­cus­sive trau­ma – inflam­ma­tion pur­suant to head trau­ma
  • Low Blood Pres­sure

We have dis­cov­ered that this pro­to­col sub­stan­tial­ly and imme­di­ate­ly improves men­tal func­tion using neu­ro­log­i­cal pan­els.


  • To max­i­mize blood deliv­ery with­in the brain to reverse inflam­ma­tion
  • To open all cap­il­lar­ies for opti­mal blood deliv­ery to brain


  • 500mg Niacin*
  • 500mg Mag­ne­sium Oro­tate
  • 500mg Vit­a­min C
  • 100mg Thi­amine (Vit­a­min B1)
  • 3000mg Argi­nine Alpha Ketog­lu­tarate

Brain Oxygenation Protocol

  1. Take sup­ple­ments and wait 20 min­utes
  2. Warm up until you reach your tar­get pulse rate (110 bpm pre­ferred using oxy­gen)
  3. Exer­cise for 8 min­utes at mod­er­ate strain
  4. Do the fol­low­ing steps 3 times:
    1. Switch to -O2 and begin a 30 sec­ond sprint
    2. Use -O2 for the first 15 sec­onds, then switch to +O2 for 15 sec­onds
    3. Recov­er on oxy­gen
    4. Do you feel like your body wants anoth­er sprint?, If so, repeat this sequence; oth­er­wise, skip to step 5 below.
    5. Stop exer­cis­ing at 15 min­utes, or when you feel like you need to stop, or when you’ve fin­ished 3 sprints
  5. Con­tin­ue breath­ing oxy­gen until your pulse rate drops to 100 bpm or less.

You can stop at any time. If you are unable to com­plete the pro­to­col, try again in a few hours or the next day. It may take sev­er­al pass­es to become strong enough to com­plete the pro­to­col. Each attempt will usu­al­ly make you sig­nif­i­cant­ly stronger and more able to con­tin­ue.

* The pur­pose of Niacin is to pro­duce a niacin flush. Research this before you start the pro­to­col. You may begin when you are ful­ly com­fort­able with the pro­to­col and under­stand what a niacin flush feels like. The niacin flush opens the blood ves­sels in the skin and head.

Oxygen Detox Protocol

This pro­to­col flush­es meta­bol­ic waste out of tis­sues. It also facil­i­tates heal­ing by super-sat­u­rat­ing all body tis­sues, plas­ma and lymph with very high lev­els of oxy­gen. It is equiv­a­lent to spend­ing many hours in a hyper­bar­ic cham­ber. It also boosts the immune sys­tem. Use this pro­to­col when you feel slug­gish, tired or just want to feel bet­ter.

  1. Exer­cise for 6–8 min­utes at a sus­tain­able but aer­o­bic pace (solid­ly aer­o­bic) (you can use -O2 to accel­er­ate the warm-up)
    • Note exer­tion chal­lenges – dis­com­fort that occurs at about 1 minute inter­vals
    • Men­tal­ly note the first chal­lenge inten­si­ty
    • Reduce effort mod­er­ate­ly dur­ing chal­lenges
    • Con­tin­ue on +O2 until chal­lenges become unno­tice­able and exer­tion is easy, usu­al­ly with­in 6 to 8 min­utes
  2. After exer­tion chal­lenges end, begin a sprint sequence
    • Switch to -O2
    • Sprint for 15 sec­onds at your high­est lev­el of exer­tion
    • Switch to +O2 and con­tin­ue the sprint for anoth­er 15 sec­onds
    • Recov­er on oxy­gen until detox clears
  3. Repeat 4 to 8 times
  4. Stop exer­cis­ing at 15 min­utes
  5. Con­tin­ue breath­ing oxy­gen until your pulse drops to 100 bpm or less.

If you start to feel sick, or feel sick with a cold, flu or oth­er immuno­log­i­cal chal­lenge (like you spent yes­ter­day on an air­plane), then you can aug­ment your immune sys­tem by tak­ing:

  • Thy­mus Extract – 2 cap­sules
  • Colostrums – 2 cap­sules
  • Cordy­ceps Sinen­sis – 2 cap­sules

Immune Boost Using a Sauna or Hot Tub

This pro­to­col is for immune chal­lenges that occur from trav­el-relat­ed stress or expo­sure to cold/flu or oth­er organ­isms that can com­pro­mise per­for­mance.

The pro­to­col tar­gets short term sat­u­ra­tion of tis­sues with oxy­gen, fol­lowed by expo­sure to heat, either in a sauna or hot tub.

Take the fol­low­ing sup­ple­ments 20 min­utes pri­or to oxy­gen ther­a­py:

  • Thy­mus Extract – 2 cap­sules — helps boost the immune sys­tem
  • Colostrums – 2 cap­sules — sup­plies immune and growth fac­tors along with a vari­ety of vit­a­mins and min­er­als
  • Cordy­ceps Sinen­sis – 2 cap­sules — helps the body resist fatigue and boosts the immune sys­tem

Immune Boost Protocol Steps

  • Take sup­ple­ments and wait 20 to 40 min­utes
  • Warm up until you reach your tar­get pulse rate
  • Put on the mask and con­nect to the oxy­gen
  • Exer­cise for 10 min­utes with mod­er­ate effort until you feel hot and start to sweat
  • Move into the sauna or hot tub, con­tin­u­ing oxy­gen use, if pos­si­ble
  • Remain in the sauna or hot tub until your body reach­es 104 degrees or tol­er­ance (do not exceed 104)
  • Exit the sauna or hot tub and cool down, con­tin­ue to breathe oxy­gen until your pulse drops below 90 bpm.

Connective Tissue

This pro­to­col accel­er­ates con­nec­tive tis­sue devel­op­ment in sit­u­a­tions where pri­or exer­cise has caused a con­nec­tive tis­sue strength imbal­ance such that the mus­cle is stronger than the tis­sue which con­nects it to the bone.


Many exer­cise meth­ods that focus on mus­cle devel­op­ment often cre­ate a strength imbal­ance between mus­cle and con­nec­tive tis­sue. In sim­ple terms, the con­nec­tive tis­sue must be able to with­stand the max­i­mum repet­i­tive jerk-ten­sion of the mus­cle with­out cumu­la­tive micro-trau­ma.

Mod­ern exer­cise meth­ods do not rec­og­nize or address the fac­tors that enable con­nec­tive tis­sue devel­op­ment. This method is based pri­mar­i­ly on the obser­va­tion that white tis­sue does not have cap­il­lar­ies.


There are two unrec­og­nized effects that deter­mine the rate of con­nec­tive tis­sue devel­op­ment ver­sus mus­cle devel­op­ment:

  • Con­nec­tive tis­sue receives oxy­gen and nutri­ents from extra-cel­lu­lar flu­ids, while mus­cle obtains nutri­ents and oxy­gen from blood;
  • Con­nec­tive tis­sue growth is stim­u­lat­ed by shock, while mus­cle devel­op­ment is stim­u­lat­ed by smooth strain.

As a result, exer­cise meth­ods that do not bal­ance these four fac­tors often pro­duce struc­ture and strength imbal­ances that result in a vul­ner­a­bil­i­ty to injury.

These effects par­tic­u­lar­ly affect large ath­letes with well devel­oped mus­cle. They often exhib­it a high­er joint-injury vul­ner­a­bil­i­ty because strong mus­cles over-stress the con­nec­tive tis­sue, result­ing in chron­ic inflam­ma­tion and ele­vat­ed con­nec­tive tis­sue injury.

Strength exer­cise meth­ods, weight lift­ing in par­tic­u­lar, increas­es mus­cle mass much more rapid­ly than con­nec­tive tis­sue strength.

This method enables spe­cial­ized devel­op­ment of con­nec­tive tis­sue strength and dura­bil­i­ty.

Principles of Method

There are two sim­ple prin­ci­ples of this exer­cise method:

  • Sat­u­rate non-vas­cu­lar body flu­ids with oxy­gen
  • Exer­cise using meth­ods that ampli­fy shock, but not smooth exer­tion.

Phys­i­cal­ly, this sug­gests the use of high oxy­gen while lift­ing mod­er­ate weight, in motion pat­terns that iso­late vul­ner­a­ble con­nec­tive tis­sue from mus­cles and lig­a­ments.

Please click “Yes” if you would engage in a com­mu­ni­ty group relat­ing to this pro­to­col. Your answer tells us which pro­to­col is most impor­tant.